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Diffusion of colognes/perfumes from skin

I have long wondered if we can create a computer model that simulates the diffusion of pheromone molecules. This model can allow us to study the diffusion and dispersion of pheromone molecules off our skin based on different application points. This is a challenging task, but not impossible. Such a model can be really useful to identify an ideal approach for pheromone application.

Its a work in progress, so I was excited to come across two papers that greatly help increase my understanding in this regard.

The first paper talks about the variation in the outer skin temperature at different locations of the body. The paper is titled "Human Calorimetry", and you can download it here.

This excerpt from the paper should be enough to pique your interest:

"In normal surroundings, say at 25°C.,the average temperature for the whole skin surface of a lightly clothed man will be in the neighborhood of 33°C.,the average being a mean of widely different temperatures at different parts of the body surface. At the fet the temperature may be as low as 27°C., while on the abdomen it may approach 35 or 36°C.The temperature, of course, rises as we advance from the skin to the interior. The experiments of Bazet and McGlone ('27) showed that in the forearm and thigh, the constant internal temperature was not reached until a depth of about 2.5 cm. was reached. Those of Benedict and Slack ('10), on the temperatures at diferent depths in the rectum and vagina, showed that constancy was not reached until a depth of 5 to 7 cm. In the view of these facts, the assumption that the average temperature is close to 37°C. cannot be made with out investigation."

The second paper "Models to assess perfume diffusion from skin" presents the creation of a tool that was developed to simulate the diffusion of perfumes from skin over time. This tool basically provided a way for researchers to replicate and vary the skin conditions as desired and study the effect they had on the applied perfumes.  They looked at several skin parameters: skin surface texture, skin hydration, trans-epidermal water loss, skin surface temperature, air movements, individual odour etc.

Here is a portion of the conclusion from the paper:

"The results clearly show that temperature, concentration, and ventilation are crucial parameters in the simulation of fragrance diffusion from skin..."

Check out the full text of the paper here.

Enjoy!


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